Study: PARPi olaparib for the targeted treatment of metastatic prostate cancer
Results from the PROfound phase III study, funded by AstraZeneca and Merck Sharp & Dohme, open up a much-needed new treatment avenue for the more precise and effective treatment of patients with metastatic castration-resistant...
Study: Caffeine shot delivers wakeup call on antifungal drug resistance
The management of fungal infections in plants and humans could be transformed by a breakthrough in understanding how fungi develop resistance to drugs.
It was previously thought that only mutations in a fungi's DNA would...
Study: One-time treatment generates new neurons, eliminates Parkinson’s disease in mice
Xiang-Dong Fu, PhD, has never been more excited about something in his entire career. He has long studied the basic biology of RNA, a genetic cousin of DNA, and the proteins that bind it....
Study: Blood pressure medications help even the frailest elderly people live longer
Taking blood pressure medication as prescribed helped even the frailest elderly people (65 and older) live longer, and the healthiest older people had the biggest survival boost, according to a large study in northern...
Research unveils many ways carcinogens trigger development of breast cancer
In the most comprehensive review to date of how breast cancer develops, scientists have created a detailed map that describes the many ways in which environmental chemicals can trigger the disease. Using ionizing radiation...
Research identifies 21 existing drugs that could treat COVID-19
A Nature study authored by a global team of scientists and led by Sumit Chanda, Ph.D., professor at Sanford Burnham Prebys Medical Discovery Institute, has identified 21 existing drugs that stop the replication of...
Study: Women taking menopausal hormone therapy may be more resistant to urine infections
In the first analysis of its kind, US-based doctors have shown that women who take menopausal hormone therapy (MHT, also known as HRT) have a greater variety of beneficial bacteria in their urine, possibly...
Study: Warning for children with chronic conditions
With stressed hospital services, and concerns about the spread of COVID-19, experts are reminding carers of children and young people of the importance of sticking to their supported chronic condition self-management plans from the...
Study: Ghrelin may be an effective treatment for age-related muscle loss
The hormone, ghrelin, may help protect the elderly population from muscle loss, according to a study being presented at e-ECE 2020. The study found that administering a particular form of ghrelin to older mice...
Scientists develop software to find drug-resistant bacteria
The program could make it easier to identify the deadly antimicrobial resistant bacteria that exist in the environment. Such microbes annually cause more than 2.8 million difficult-to-treat pneumonia, bloodstream and other infections and 35,000...